Glutathione for Eczema

Glutathione is a powerful antioxidant with many benefits for overall health, including skin benefits. But what effect, if any, can it have on eczema? 

 In this article, we will explore the potential benefits of glutathione for eczema and whether it is a viable treatment option for those suffering from this condition. 

What Is Glutathione?

Glutathione is a powerful antioxidant that is naturally produced by the body. It plays a crucial role in protecting cells from damage caused by free radicals and toxins. Glutathione is made up of three amino acids: cysteine, glutamic acid, and glycine. It is found in high concentrations in the liver, where it helps to detoxify harmful substances.

Glutathione has been shown to have a number of health benefits, including reducing inflammation, boosting the immune system, and improving skin health. It is also believed to be effective in treating a range of conditions, including eczema. You can learn more about glutathione here.

Understanding Eczema

There are several types of eczema, including atopic dermatitis, contact dermatitis, and nummular eczema. Atopic dermatitis is the most common type of eczema, affecting up to 25% of children and 2-3% of adults. Contact dermatitis occurs when the skin comes into contact with an irritant or allergen, while coin-shaped patches of irritated skin characterize nummular eczema.

 It is characterized by dry, itchy, inflamed skin that can be painful, and uncomfortable. Eczema can occur at any age but is most common in children. The exact cause of eczema is unknown, but it is believed to be a combination of genetic and environmental factors.

A variety of factors, including stress, certain foods, environmental allergens, and harsh chemicals, can trigger eczema. Symptoms of eczema can range from mild to severe and can include redness, itching, dryness, and flaking of the skin.

While there is no cure for eczema, there are several treatments available to help manage symptoms. These include topical creams and ointments, oral medications, and lifestyle changes such as avoiding triggers and maintaining good skin hygiene.

In recent years, there has been growing interest in the use of glutathione as a treatment for eczema. Glutathione is a powerful antioxidant that is naturally produced by the body. It plays a crucial role in protecting cells from damage caused by free radicals and toxins.

Research has shown that people with eczema have lower glutathione levels than those without the condition. This has led to speculation that increasing glutathione levels may help alleviate eczema symptoms.

How Glutathione Can Help with Eczema

Glutathione is a powerful antioxidant that plays a crucial role in protecting the body from oxidative stress and inflammation. It is naturally produced by the body, but its levels can be depleted by various factors such as stress, pollution, and poor diet; these factors lead to oxidative stress. Glutathione has been found to have numerous benefits for the skin, including its potential to alleviate eczema symptoms.

One of the ways that glutathione can help with eczema is by reducing oxidative stress and inflammation in the body. Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body, leading to damage to cells and tissues. 

Inflammation is the body’s natural response to injury or infection, but chronic inflammation can contribute to the development and progression of various diseases, including eczema.

Glutathione can help reduce oxidative stress and inflammation by neutralizing free radicals and promoting the production of other antioxidants in the body. It can also help regulate the immune system, which plays a crucial role in the development and progression of eczema.

In addition to its antioxidant and anti-inflammatory properties, glutathione has also been found to have a direct effect on the skin. It can help improve skin hydration, elasticity, and overall appearance. This is because glutathione helps promote the production of collagen, a protein that is essential for healthy skin.

Overall, glutathione has the potential to be a valuable addition to eczema treatment. However, it is important to note that more research is needed to fully understand its effects on eczema and to determine the optimal dosage and duration of treatment. It is also important to consult with a healthcare professional before starting any new treatment, including glutathione supplements.

Scientific Studies on Glutathione and Eczema

There’s a wide body of research confirming the effectiveness of glutathione in treating eczema. 

One study published in the Journal of Dermatological Science found that glutathione supplementation improved the symptoms of atopic dermatitis, a type of eczema, in mice. The study concluded that glutathione may be a promising therapeutic option for atopic dermatitis.

Another study published in the Journal of Investigative Dermatology found that glutathione levels were significantly lower in the skin of patients with atopic dermatitis compared to healthy individuals. The study suggests that glutathione deficiency may play a role in the development of atopic dermatitis and that increasing glutathione levels may be a potential treatment option.

This study found that topical application of glutathione reduced the severity of eczema symptoms in patients. The study concluded that glutathione may be a safe and effective treatment option for eczema.

Overall, these studies suggest that glutathione may be a promising natural treatment option for eczema. However, more research is needed to fully understand the effectiveness of glutathione for eczema treatment.

It is important to note that while these studies show promising results, they were conducted on a small scale and may not be representative of the general population. It is always recommended to consult with a healthcare professional before starting any new treatment for eczema.

Personal Experiences with Glutathione for Eczema

A year ago I experienced an eczema flair on my face and neck. It was my first occurrence; I don’t recal having eczema as a child, when it’s most common. 

For a period of six months, I had a cycle of flairups, some more severe than others. During the last episode, I received an injection of glutathione. I noticed a slight improvement within 24 hours. The scaly patches became less inflamed. 

I also applied CereVe Itch Relief Moisturizing Lotion, which has pramoxine hydrochloride 1%, an effective treatment for itching. This was very effective in relieving the itching and burning feeling. I also applied vaseline to the scaly areas. 

After a week, my symptoms disappeared and I haven’t experienced another flairup since.

I can’t say weather the glutathione or the CereVe lotion and other moisturizers were more effective in my healing, but I suspect both of them helped. 

I don’t think glutathione on it’s own would have reduced the itchiness. But I do think it helped to reduce the inflammation overall. 

Glutathione Supplements for Eczema

Gluthathione comes in many forms: topical creams, pills and IVs or injections. I cover the effectiveness of these forms in this article

In summary, glutathione injections or IV are the most effective way to get glutathione into your bloodstream. Oral forms of gluthione are mostly destroyed in the digestive track, so not much of it gets absorbed by your body. 

Although studies support glutathione creams help with certain skin conditions like eczema, effectiveness depends on the formulation.

Other Natural Remedies for Eczema

While glutathione has shown promise in alleviating eczema symptoms, there are also other natural remedies that can be used in conjunction with or instead of glutathione. Here are some options to consider:


Studies have shown that probiotics can improve eczema symptoms by balancing the gut microbiome and reducing inflammation. Look for probiotic supplements or foods like yogurt, kefir, and sauerkraut.

Omega-3 fatty acids

These healthy fats can reduce inflammation and improve skin health. Sources include fatty fish like salmon, chia seeds, and flaxseed oil.

Vitamin D

Low levels of vitamin D have been linked to eczema, so getting enough of this nutrient may help improve symptoms. Sun exposure is the best source of vitamin D, but supplements are also available.

Aloe vera

This plant has anti-inflammatory properties and can soothe irritated skin. Look for pure aloe vera gel or creams containing aloe vera.

Colloidal oatmeal

This finely ground oatmeal can be added to baths or used in creams to relieve itching and inflammation.

It’s important to note that natural remedies may not work for everyone, and it’s always a good idea to talk to a healthcare provider before trying any new treatments.  

Additionally, some natural remedies may interact with medications or cause allergic reactions, so it’s important to use caution and do your research before trying them.

Precautions and Side Effects of Glutathione

Symptoms of eczema can look like other skin disorders, so it’s important to get a firm diagnosis to find the appropriate treatment.

Glutathione is naturally produced in our bodies, so it’s considered safe. An overdose of glutathione is extremely rare as our bodies process it very quickly.

While glutathione is generally considered safe for most people, there are some precautions and potential side effects to be aware of when using it for eczema.

Firstly, it is important to note that glutathione supplements are not regulated by the FDA, so choose a reputable brand and consult with a healthcare professional before starting any new supplement regimen.

Additionally, some people may experience mild side effects such as nausea, stomach upset, or diarrhea when taking glutathione supplements. These side effects are usually temporary and can be minimized by taking the supplement with food or reducing the dosage.

Glutathione supplements may interact with certain medications so it is important to inform your healthcare provider if you are taking any medications before starting a glutathione supplement.

Is Glutathione The Right Treatment for Your Eczema?

While glutathione has shown promising results in managing eczema symptoms, it may not be the best solution for everyone. 

It is always recommended to consult with a healthcare professional before starting any new treatment or supplement regimen.

Consider combining it with other remedies for eczema, such as moisturizing regularly, avoiding triggers, and maintaining a healthy diet. These remedies may work in conjunction with glutathione to provide the best results.

In conclusion, glutathione has shown promising results in managing eczema symptoms by reducing inflammation and combating oxidative stress. It may be a natural and effective solution for some individuals. 

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Ann Bertholf

Ann is a skincare geek, product tester and ingredient sleuth. She looks past the marketing hype and searches for effective, evidence based ingredients and formulations. She is a writer and cat mom.

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